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ABSTRACT: Background
fact Boxes are decision support tools that can inform about treatment effects.Objectives
to test whether Fact Box decision support tools impacted decisional conflict, knowledge and preferences about the use of antibiotics and artificial hydration in advanced dementia.Design
randomized controlled trial.Setting
Swiss-German region of Switzerland.Subjects
two hundred thirty-two participants (64 physicians, 100 relatives of dementia patients, 68 professional guardians) randomly allocated to intervention (N = 114) or control (N = 118).Intervention
two-page Fact Box decision support tools on antibiotics for pneumonia and artificial hydration in advanced dementia (at 1-month).Methods
participants were mailed questionnaires at baseline and one month later that asked questions about treatments based on hypothetical scenarios. The primary outcome was change in decisional conflict (DCS-D; range 0 < 100) about treatment decisions. Secondary outcomes included knowledge about treatments (range 0 < 7) and preferences to forego treatments.Results
participants were: mean age, 55.6 years; female, 62.8%. Relative to control participants, intervention participants experienced less decisional conflict about using antibiotics (unstandardized beta (b) = -8.35, 95% Confidence Interval (CI), -12.43, -4.28) and artificial hydration (b = -6.02, 95% CI, -9.84, -2.20) at 1-month compared to baseline. Intervention participants displayed greater knowledge about the use of antibiotics (b = 2.24, 95% CI, 1.79, 2.68) and artificial hydration (b = 3.01, 95% CI, 2.53, 3.49), and were significantly more likely to prefer to forego antibiotics (odds ratio, 2.29, 95% CI, 1.08, 4.84) but not artificial hydration.Conclusions
fact Box decision support tools reduced decisional conflict, increased knowledge and promoted preferences to forego antibiotics in advanced dementia among various decision-makers.Trial registration
FORSbase (12091).
SUBMITTER: Loizeau AJ
PROVIDER: S-EPMC6322502 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Loizeau Andrea J AJ Theill Nathan N Cohen Simon M SM Eicher Stefanie S Mitchell Susan L SL Meier Silvio S McDowell Michelle M Martin Mike M Riese Florian F
Age and ageing 20190101 1
<h4>Background</h4>fact Boxes are decision support tools that can inform about treatment effects.<h4>Objectives</h4>to test whether Fact Box decision support tools impacted decisional conflict, knowledge and preferences about the use of antibiotics and artificial hydration in advanced dementia.<h4>Design</h4>randomized controlled trial.<h4>Setting</h4>Swiss-German region of Switzerland.<h4>Subjects</h4>two hundred thirty-two participants (64 physicians, 100 relatives of dementia patients, 68 pro ...[more]