Ontology highlight
ABSTRACT:
SUBMITTER: Li F
PROVIDER: S-EPMC6322876 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Li Fangfang F Lang Yange Y Ji Zhenglin Z Xia Zhiqiang Z Han Yuewen Y Cheng Yuting Y Liu Gaomin G Sun Fang F Zhao Yonghui Y Gao Minjun M Chen Zongyun Z Wu Yingliang Y Li Wenxin W Cao Zhijian Z
The Journal of biological chemistry 20181107 1
Viral infections still threaten human health all over the world, and many people die from viral diseases every year. However, there are no effective vaccines or drugs for preventing or managing most viral diseases. Thus, the discovery and development of broad-spectrum antiviral agents remain urgent. Here, we expressed and purified a venom peptide, Ev37, from the scorpion <i>Euscorpiops validus</i> in a prokaryotic system. We found that rEv37 can inhibit dengue virus type 2 (DENV-2), hepatitis C ...[more]