Dataset Information

Vitamin D status and its determinants in healthy pregnant women living in Switzerland in the first trimester of pregnancy.

ABSTRACT:

Objectives

Our study aimed at assessing the prevalence and determinants of vitamin D deficiency (25-hydroxy-vitamin D [25(OH)D]?MethodsFrom September 2014 through December 2015, 204 pregnant women were conveniently recruited during their first clinical appointment at the Clinic of Obstetrics of the University Hospital Zurich (between week 6 and 12 of pregnancy). Blood samples were collected and a questionnaire focusing on lifestyle and skin colour was completed face-to-face with the responsible physician. Logistic regression analyses were performed with vitamin D status as dependent variable.

Results

63.2% of the participating women were vitamin D deficient, and the median vitamin D concentration in the overall sample was 17.1?ng/mL [Q1, Q3: 9.78, 22.3]. The highest proportions of vitamin D deficiency were detected in women originating from Africa and Middle East (91.4% deficient, median vitamin D concentration of 10.7?ng/mL [Q1, Q3: 6.55, 14.45]) and from South-East Asia/Pacific (88.5% deficient, median vitamin D concentration of 8.4?ng/mL [Q1, Q3: 6.10, 14.88]). Multivariable logistic regression showed that significant risk factors of vitamin D deficiency were country of origin (women born in Switzerland and Germany had a lower risk than women born in other countries), smoking status (lower risk for former smokers) and intake of vitamin D supplements.

Conclusions

Our results confirm a high prevalence of vitamin D deficiency in this Swiss cohort, in particular in women coming from Asian and African countries, and underline the importance of appropriate counseling and vitamin D supplementation in early pregnancy.

SUBMITTER: Cabaset S

PROVIDER: S-EPMC6323787 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Publications

Vitamin D status and its determinants in healthy pregnant women living in Switzerland in the first trimester of pregnancy.

Cabaset Sophie S Krieger Jean-Philippe JP Richard Aline A Elgizouli Magdeldin M Nieters Alexandra A Rohrmann Sabine S Quack Lötscher Katharina C KC

BMC pregnancy and childbirth 20190108 1

<h4>Objectives</h4>Our study aimed at assessing the prevalence and determinants of vitamin D deficiency (25-hydroxy-vitamin D [25(OH)D] < 20 ng/mL) in pregnant women in the first trimester living in Switzerland.<h4>Methods</h4>From September 2014 through December 2015, 204 pregnant women were conveniently recruited during their first clinical appointment at the Clinic of Obstetrics of the University Hospital Zurich (between week 6 and 12 of pregnancy). Blood samples were collected and a question ...[more]

PMID: 30621626

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Dataset Information

Vitamin D status and its determinants in healthy pregnant women living in Switzerland in the first trimester of pregnancy.

Objectives

Results

Conclusions

Publications

Vitamin D status and its determinants in healthy pregnant women living in Switzerland in the first trimester of pregnancy.

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