RNAct: Protein-RNA interaction predictions for model organisms with supporting experimental data.
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ABSTRACT:
SUBMITTER: Lang B
PROVIDER: S-EPMC6324028 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
RNAct: Protein-RNA interaction predictions for model organisms with supporting experimental data.
Lang Benjamin B Armaos Alexandros A Tartaglia Gian G GG
Nucleic acids research 20190101 D1
Protein-RNA interactions are implicated in a number of physiological roles as well as diseases, with molecular mechanisms ranging from defects in RNA splicing, localization and translation to the formation of aggregates. Currently, ∼1400 human proteins have experimental evidence of RNA-binding activity. However, only ∼250 of these proteins currently have experimental data on their target RNAs from various sequencing-based methods such as eCLIP. To bridge this gap, we used an established, computa ...[more]
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