Association of Medication Intensity and Stages of Airflow Limitation With the Risk of Hospitalization or Death in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease.

ABSTRACT:

Importance

In heart failure (HF), chronic obstructive pulmonary disease (COPD) increases the risk of poor outcomes, but the effect of COPD severity is unknown. This information is important for early intervention tailored to the highest-risk groups.

Objectives

To determine the associations between COPD medication intensity or stage of airflow limitation and the risk of hospitalization or death in patients with HF.

Design, setting, and participants

This UK population-based, nested case-control study with risk-set sampling used the Clinical Practice Research Datalink linked to Hospital Episode Statistics between January 1, 2002, to January 1, 2014. Participants included patients aged 40 years and older with a new diagnosis of HF in their family practice clinical record.

SUBMITTER: Lawson CA 

PROVIDER: S-EPMC6324325 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature