Genetic Correlation of Antibiotic Susceptibility and Resistance Genotyping for the Mycobacterium abscessus Group.
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ABSTRACT:
SUBMITTER: Zheng H
PROVIDER: S-EPMC6325201 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
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Genetic Correlation of Antibiotic Susceptibility and Resistance Genotyping for the <i>Mycobacterium abscessus</i> Group.
Zheng Huiwen H Liu Dongxin D Lu Jie J Song Yuanyuan Y Wang Shengfen S Zhao Yanlin Y Ni Xin X
Antimicrobial agents and chemotherapy 20181221 1
Treatment efficacy of <i>Mycobacterium abscessus</i> infections depends on bacterial genotype. Here, the relationship between genotype, as determined by sequence analysis, and antibiotic resistance phenotype was analyzed. The results demonstrate that <i>M. abscessus</i> genotype characteristics, including <i>erm</i>(41) sequevar and mutations of <i>rrl</i> and <i>rrs</i>, are predictive of clarithromycin and amikacin resistance. ...[more]
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