Ontology highlight
ABSTRACT:
SUBMITTER: Lumaka A
PROVIDER: S-EPMC6325645 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Lumaka Aimé A Race Valerie V Peeters Hilde H Corveleyn Anniek A Coban-Akdemir Zeynep Z Jhangiani Shalini N SN Song Xiaofei X Mubungu Gerrye G Posey Jennifer J Lupski James R JR Vermeesch Joris R JR Lukusa Prosper P Devriendt Koenraad K
American journal of medical genetics. Part A 20180808 9
Pathogenic variants account for 4 to 41% of patients with intellectual disability (ID) or developmental delay (DD). In Sub-Saharan Africa, the prevalence of ID is thought to be higher, but data in Central Africa are limited to some case reports. In addition, clinical descriptions of some syndromes are not available for this population. This study aimed at providing an estimate for the fraction of ID/DD for which an underlying etiological genetic cause may be elucidated and provide insights into ...[more]