Ontology highlight
ABSTRACT:
SUBMITTER: Park AR
PROVIDER: S-EPMC6325692 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Genetics 20181115 1
Heterochromatin protein 1a (HP1a) is a highly conserved and versatile epigenetic factor that can both silence and activate transcription. However, the function of HP1a in development has been underinvestigated. Here, we report the role of maternal HP1a in producing maternal transcripts that drive early <i>Drosophila</i> embryogenesis. Maternal HP1a upregulates genes involved in translation, mRNA splicing, and cell division, but downregulates genes involved in neurogenesis, organogenesis, and ger ...[more]