Ontology highlight
ABSTRACT:
SUBMITTER: Compaore TR
PROVIDER: S-EPMC6326155 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Compaore Tegwinde Rebeca TR Soubeiga Serge Theophile ST Ouattara Abdoul Karim AK Tchelougou Damehan D Bisseye Cyrille C Bakouan Didier Romuald DR Compaore Issaka I Dembele Augustine A Yonli Albert Theophane AT Obiri-Yeboah Dorcas D Djigma Wendkuuni Florencia WF Simpore Jacques J
Journal of public health in Africa 20181221 3
APOBEC3G is a potent inhibitor of HIV-1 replication, and act by deaminating cytidines in uracil on the negative strand of the viral cDNA. In this case-control study, <i>APOBEC3G</i> expression in subjects' naïve to HAART infected by HIV-1 and the effect of APOBEC3G polymorphism on its expression were evaluated. The results show that the HIV-1 infected carriers of the G minor alleles of the variant rs8177832 had a higher expression of <i>APOBEC3G</i> mRNA than the controls carriers of the G minor ...[more]