Ontology highlight
ABSTRACT:
SUBMITTER: Price RL
PROVIDER: S-EPMC6326515 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Price R L RL Bugeon L L Mostowy S S Makendi C C Wren B W BW Williams H D HD Willcocks S J SJ
PloS one 20190109 1
Antimicrobial peptides (AMP), part of the innate immune system, are well studied for their ability to kill pathogenic microorganisms. However, many also possess important immunomodulatory effects, and this area has potential for the development of novel therapies to supplement traditional methods such as the use of antibiotics. Here, we characterise the microbicidal and immunomodulatory potential of the proline-rich bovine AMP, Bactenecin 5 (Bac5). We demonstrate broad antimicrobial activity, in ...[more]