Ontology highlight
ABSTRACT:
SUBMITTER: Lucarelli G
PROVIDER: S-EPMC6326659 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Lucarelli Giuseppe G Rutigliano Monica M Sallustio Fabio F Ribatti Domenico D Giglio Andrea A Lepore Signorile Martina M Grossi Valentina V Sanese Paola P Napoli Anna A Maiorano Eugenio E Bianchi Cristina C Perego Roberto A RA Ferro Matteo M Ranieri Elena E Serino Grazia G Bell Lauren N LN Ditonno Pasquale P Simone Cristiano C Battaglia Michele M
Aging 20181201 12
An altered metabolism is involved in the development of clear cell - renal cell carcinoma (ccRCC), and in this tumor many altered genes play a fundamental role in controlling cell metabolic activities. We delineated a large-scale metabolomic profile of human ccRCC, and integrated it with transcriptomic data to connect the variations in cancer metabolism with gene expression changes. Moreover, to better analyze the specific contribution of metabolic gene alterations potentially associated with tu ...[more]