Ontology highlight
ABSTRACT:
SUBMITTER: Patel RB
PROVIDER: S-EPMC6327844 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Annual review of pharmacology and toxicology 20181008
Heart failure with preserved ejection fraction (HFpEF) accounts for over half of prevalent heart failure (HF) worldwide, and prognosis after hospitalization for HFpEF remains poor. Due, at least in part, to the heterogeneous nature of HFpEF, drug development has proved immensely challenging. Currently, there are no universally accepted therapies that alter the clinical course of HFpEF. Despite these challenges, important mechanistic understandings of the disease have revealed that the pathophysi ...[more]