Ontology highlight
ABSTRACT:
SUBMITTER: Kubota K
PROVIDER: S-EPMC6328594 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Kubota Koji K Seo Tamae T Koide Katsumasa K Hasegawa Yasuchika Y Ito Hajime H
Nature communications 20190110 1
Palladium-catalyzed cross-coupling reactions are one of the most powerful and versatile methods to synthesize a wide range of complex functionalized molecules. However, the development of solid-state cross-coupling reactions remains extremely limited. Here, we report a rational strategy that provides a general entry to palladium-catalyzed Buchwald-Hartwig cross-coupling reactions in the solid state. The key finding of this study is that olefin additives can act as efficient molecular dispersants ...[more]