Early diuretic use and mortality in critically ill patients with vasopressor support: a propensity score-matching analysis.
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ABSTRACT: Background
The effect of loop diuretic use in critically ill patients on vasopressor support or in shock is unclear. This study aimed to explore the relationship between loop diuretic use and hospital mortality in critically ill patients with vasopressor support.Methods
Data were extracted from the Medical Information Mart for Intensive Care III database. Adult patients with records of vasopressor use within 48 h after intensive care unit admission were screened. Multivariable logistic regression and propensity score matching was used to investigate any association.Results
Data on 7828 patients were included. The crude hospital mortality was significantly lower in patients with diuretic use (166/1469 vs. 1171/6359, p?ConclusionsAlthough residual confounding cannot be excluded, loop diuretic use is associated with lower mortality.
SUBMITTER: Shen Y
PROVIDER: S-EPMC6329160 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
Early diuretic use and mortality in critically ill patients with vasopressor support: a propensity score-matching analysis.
Shen Yanfei Y Zhang Weimin W Shen Yong Y
Critical care (London, England) 20190110 1
<h4>Background</h4>The effect of loop diuretic use in critically ill patients on vasopressor support or in shock is unclear. This study aimed to explore the relationship between loop diuretic use and hospital mortality in critically ill patients with vasopressor support.<h4>Methods</h4>Data were extracted from the Medical Information Mart for Intensive Care III database. Adult patients with records of vasopressor use within 48 h after intensive care unit admission were screened. Multivariable lo ...[more]
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