Ontology highlight
ABSTRACT:
SUBMITTER: Xie F
PROVIDER: S-EPMC6330258 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Xie Fang F Cai Huawei H Peng Fangyu F
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20180713 6
Copper 8-hydroxyquinoline-2-carboxaldehyde-thiosemicarbazide complex (CuHQTS) is a copper complex with strong anticancer activity against cisplatin-resistant neuroblastoma and prostate cancer cells in vitro by cell proliferation assay or fluorescent microscopic imaging. This study aimed to evaluate anti-prostate cancer activity of CuHQTS in vivo by bioluminescence imaging (BLI) and tumor size measurement, using athymic nu/nu mice implanted with prostate cancer cells carrying luciferase reporter ...[more]