Identification of N-Acetyldopamine Dimers from the Dung Beetle Catharsius molossus and Their COX-1 and COX-2 Inhibitory Activities.
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ABSTRACT:
SUBMITTER: Lu J
PROVIDER: S-EPMC6331819 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Publications
Identification of N-Acetyldopamine Dimers from the Dung Beetle Catharsius molossus and Their COX-1 and COX-2 Inhibitory Activities.
Lu Juan J Sun Qin Q Tu Zheng-Chao ZC Lv Qing Q Shui Pi-Xian PX Cheng Yong-Xian YX
Molecules (Basel, Switzerland) 20150827 9
Recent studies focusing on identifying the biological agents of Catharsius molossus have led to the identification of three new N-acetyldopamine dimers molossusamide A-C (1-3) and two known compounds 4 and 5. The structures of the new compounds were identified by comprehensive spectroscopic evidences. Compound 4 was found to have inhibitory effects towards COX-1 and COX-2. ...[more]
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