Ontology highlight
ABSTRACT:
SUBMITTER: Korabecny J
PROVIDER: S-EPMC6331912 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20151210 12
Alzheimer's disease (AD) is a debilitating progressive neurodegenerative disorder that ultimately leads to the patient's death. Despite the fact that novel pharmacological approaches endeavoring to block the neurodegenerative process are still emerging, none of them have reached use in clinical practice yet. Thus, palliative treatment represented by acetylcholinesterase inhibitors (AChEIs) and memantine are still the only therapeutics used. Following the multi-target directed ligands (MTDLs) str ...[more]