MiRNA Stability in Frozen Plasma Samples.
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ABSTRACT:
SUBMITTER: Balzano F
PROVIDER: S-EPMC6331950 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Publications
miRNA Stability in Frozen Plasma Samples.
Balzano Francesca F Deiana Marta M Dei Giudici Silvia S Oggiano Annalisa A Baralla Angela A Pasella Sara S Mannu Andrea A Pescatori Mario M Porcu Baingio B Fanciulli Giuseppe G Zinellu Angelo A Carru Ciriaco C Deiana Luca L
Molecules (Basel, Switzerland) 20151020 10
MicroRNAs (miRNAs) represent a family of small non-coding ribonucleic acids that post-transcriptionally inhibits the expression of their target messenger RNAs (mRNAs), thereby acting as general gene repressors. In this study we examined the relative quantity and stability of miRNA subjected to a long period of freezing; we compared the stability of eight miRNAs in the plasma of five human healthy controls before freezing and after six and 12 months of storage at -80 °C. In addition, we examined ...[more]
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