Ontology highlight
ABSTRACT:
SUBMITTER: Oliva R
PROVIDER: S-EPMC6332208 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Oliva Romina R Chermak Edrisse E Cavallo Luigi L
Molecules (Basel, Switzerland) 20150701 7
In view of the increasing interest both in inhibitors of protein-protein interactions and in protein drugs themselves, analysis of the three-dimensional structure of protein-protein complexes is assuming greater relevance in drug design. In the many cases where an experimental structure is not available, protein-protein docking becomes the method of choice for predicting the arrangement of the complex. However, reliably scoring protein-protein docking poses is still an unsolved problem. As a con ...[more]