Ontology highlight
ABSTRACT:
SUBMITTER: Lim SM
PROVIDER: S-EPMC6333965 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Lim Sun Min SM Cho Sang Hee SH Hwang In Gyu IG Choi Jae Woo JW Chang Hyun H Ahn Myung-Ju MJ Park Keon Uk KU Kim Ji-Won JW Ko Yoon Ho YH Ahn Hee Kyung HK Cho Byoung Chul BC Nam Byung-Ho BH Chun Sang Hoon SH Hong Ji Hyung JH Kwon Jung Hye JH Choi Jong Gwon JG Kang Eun Joo EJ Yun Tak T Lee Keun-Wook KW Kim Joo-Hang JH Kim Jin Soo JS Lee Hyun Woo HW Kim Min Kyoung MK Jung Dongmin D Kim Ji Eun JE Keam Bhumsuk B Yun Hwan Jung HJ Kim Sangwoo S Kim Hye Ryun HR
Cancer research and treatment 20180509 1
<h4>Purpose</h4>Head and neck squamous cell carcinoma (HNSCC) is a deadly disease in which precision medicine needs to be incorporated. We aimed to implement next-generation sequencing (NGS) in determining actionable targets to guide appropriate molecular targeted therapy in HNSCC patients.<h4>Materials and methods</h4>Ninety-three tumors and matched blood samples underwent targeted sequencing of 244 genes using the Illumina HiSeq 2500 platform with an average depth of coverage of greater than 1 ...[more]