Ontology highlight
ABSTRACT:
SUBMITTER: Keilholz U
PROVIDER: S-EPMC6335739 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Keilholz Ulrich U Mehnert Janice M JM Bauer Sebastian S Bourgeois Hugues H Patel Manish R MR Gravenor Donald D Nemunaitis John J JJ Taylor Matthew H MH Wyrwicz Lucjan L Lee Keun-Wook KW Kasturi Vijay V Chin Kevin K von Heydebreck Anja A Gulley James L JL
Journal for immunotherapy of cancer 20190116 1
<h4>Background</h4>We report phase 1b data from patients enrolled in the JAVELIN Solid Tumor clinical trial (NCT01772004) with unresectable stage IIIC or IV melanoma that had progressed after ≥1 line of therapy for metastatic disease.<h4>Patients and methods</h4>Patients received avelumab (10 mg/kg)-a human anti-PD-L1 antibody. Assessments included objective response rate (ORR), progression-free survival (PFS), overall survival (OS), and safety.<h4>Results</h4>As of December 31, 2016, 51 patient ...[more]