Ontology highlight
ABSTRACT:
SUBMITTER: Oliva M
PROVIDER: S-EPMC6336003 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Oliva M M Spreafico A A Taberna M M Alemany L L Coburn B B Mesia R R Siu L L LL
Annals of oncology : official journal of the European Society for Medical Oncology 20190101 1
Anti-programmed cell death protein 1 (PD-1) agents have become the standard of care for platinum-refractory recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) and are currently being evaluated in various disease settings. However, despite the gain in overall survival seen in some of the clinical trials, the majority of patients display primary resistance and do not benefit from these agents. Taking into consideration the potentially severe immune-related toxicities and their high ...[more]