Ontology highlight
ABSTRACT:
SUBMITTER: Kyle CT
PROVIDER: S-EPMC6336531 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Kyle Colin T CT Permenter Michele R MR Vogt Julie A JA Rapp Peter R PR Barnes Carol A CA
Neuromodulation : journal of the International Neuromodulation Society 20180717 4
<h4>Background</h4>Ensemble recording methods are pervasive in basic and clinical neuroscience research. Invasive neural implants are used in patients with drug resistant epilepsy to localize seizure origin, in neuropsychiatric or Parkinson's patients to alleviate symptoms via deep brain stimulation, and with animal models to conduct basic research. Studies addressing the brain's physiological response to chronic electrode implants demonstrate that the mechanical trauma of insertion is followed ...[more]