Ontology highlight
ABSTRACT:
SUBMITTER: Cui HX
PROVIDER: S-EPMC6337101 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Cui Hong-Xin HX Hu Ya-Nan YN Li Jing-Wan JW Yuan Ke K Guo Ying Y
Molecules (Basel, Switzerland) 20181228 1
Berberine has many pharmacological effects, such as antidiabetic, antimicrobial, anti-inflammatory, and antioxidant, but the question remains on how its low oral bioavailability has greatly limited its clinical application. As a safer hypoglycemic agent, we must evaluate the bioavailability of berberine organic acid salts (BOAs) to ensure that the bioavailability of berberine is not negatively affected. It has been proven that the bioavailability of BOAs is higher than that of BH (berberine hydr ...[more]