Unknown

Dataset Information

0

Biological Activities and Chemical Composition of Santolina africana Jord. et Fourr. Aerial Part Essential Oil from Algeria: Occurrence of Polyacetylene Derivatives.


ABSTRACT: The chemical composition of 18 oil samples of Santolina africana isolated from aerial parts at full flowering, collected in three locations in eastern Algeria was determined by GC(RI), GC/MS and 13C-NMR analysis. The major components were: germacrene D, myrcene, spathulenol, ?-bisabolol, ?-pinene, 1,8-cineole, cis-chrysanthenol, capillene, santolina alcohol, camphor, terpinen-4-ol and lyratol. The chemical composition appeared homogeneous and characterized by the occurrence of four derivatives which exhibited a conjugated alkene dialkyne moiety. They were identified for the first time in an essential oil from S. africana. The collective oil sample exhibited moderate antimicrobial and antioxidant activities whereas the anti-inflammatory activity presented a real potential. IC50 value of Santolina africana essential oil (0.065 ± 0.004 mg/mL) is 5-fold higher than IC50 value of NDGA used as positive control.

SUBMITTER: Malti CEW 

PROVIDER: S-EPMC6337488 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

Biological Activities and Chemical Composition of <i>Santolina africana</i> Jord. et Fourr. Aerial Part Essential Oil from Algeria: Occurrence of Polyacetylene Derivatives.

Malti Charaf Eddine Watheq CEW   Baccati Clémentine C   Mariani Magali M   Hassani Faiçal F   Babali Brahim B   Atik-Bekkara Fewzia F   Paoli Mathieu M   Maury Jacques J   Tomi Félix F   Bekhechi Chahrazed C  

Molecules (Basel, Switzerland) 20190108 1


The chemical composition of 18 oil samples of <i>Santolina africana</i> isolated from aerial parts at full flowering, collected in three locations in eastern Algeria was determined by GC(RI), GC/MS and <sup>13</sup>C-NMR analysis. The major components were: germacrene D, myrcene, spathulenol, α-bisabolol, β-pinene, 1,8-cineole, <i>cis</i>-chrysanthenol, capillene, santolina alcohol, camphor, terpinen-4-ol and lyratol. The chemical composition appeared homogeneous and characterized by the occurre  ...[more]

Similar Datasets

| S-EPMC6273290 | biostudies-literature
| S-EPMC8145663 | biostudies-literature
| S-EPMC7150886 | biostudies-literature
| S-EPMC6768038 | biostudies-literature
| S-EPMC5068741 | biostudies-literature
| S-EPMC7465808 | biostudies-literature
| S-EPMC5020101 | biostudies-literature
| S-EPMC5541024 | biostudies-literature
2012-09-03 | GSE37284 | GEO
2012-09-03 | GSE37285 | GEO