Ontology highlight
ABSTRACT:
SUBMITTER: Wu J
PROVIDER: S-EPMC6337550 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20190108 1
Major depressive disorder is now becoming a common disease in daily life, and most patients do not have satisfactory treatment outcomes. We herein evaluated the therapeutic effects of Zhile capsule and clarified the molecular mechanism. A rat model of chronic unpredictable mild stress-induced depression was established to assess the antidepressant-like effects of Zhile by using the sucrose preference test, open field test, forced swim test, tail suspension test and HPLC. Systems pharmacology was ...[more]