Symbiont-derived sphingolipids regulate inflammatory responses in rainbow trout (Oncorhynchus mykiss).
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ABSTRACT:
SUBMITTER: Sanchez M
PROVIDER: S-EPMC6338430 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
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Symbiont-derived sphingolipids regulate inflammatory responses in rainbow trout (<i>Oncorhynchus mykiss</i>).
Sanchez Mariah M Sepahi Ali A Casadei Elisa E Salinas Irene I
Aquaculture. 20180531
Farmed fish live in association with diverse bacterial communities that produce wide arrays of metabolites. In rainbow trout, the skin and the gills are colonized by <i>Flectobacillus major</i>, a bacterium known to produce sphingolipids (SLs). The goal of this study is to evaluate the ability of <i>F. major</i> SLs to regulate rainbow trout inflammatory responses. <i>F. major</i> SLs were delivered by themselves or in combination with Freund's Complete Adjuvant (FCA), an oil-based adjuvant know ...[more]
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