Ontology highlight
ABSTRACT:
SUBMITTER: Dardiotis E
PROVIDER: S-EPMC6340332 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Dardiotis Efthimios E Panayiotou Elena E Siokas Vasileios V Aloizou Athina-Maria AM Christodoulou Kyproula K Hadjisavvas Andreas A Pantzaris Marios M Grigoriadis Nikolaos N Hadjigeorgiou Georgios M GM Kyriakides Theodoros T
Neurology. Genetics 20190116 1
<h4>Objective</h4>To examine the effect of variants in genes encoding molecules that are implicated in leukocyte trafficking into the CNS on the development of MS.<h4>Methods</h4>A total of 389 Greek MS cases and 336 controls were recruited by 3 MS centers in Cyprus and Greece. In total, 147 tagging single nucleotide polymorphisms across 9 genes encoding for P-selectin (<i>SELP</i>), integrins (<i>ITGA4</i>, <i>ITGB1</i>, and <i>ITGB7</i>), adhesion molecules (<i>ICAM1</i>, <i>VCAM1</i>, and <i> ...[more]