Ontology highlight
ABSTRACT:
SUBMITTER: Niarchou M
PROVIDER: S-EPMC6341088 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Translational psychiatry 20190116 1
Deletion and duplication of 16p11.2 (BP4-BP5) have been associated with an increased risk of intellectual disability and psychiatric disorder. This is the first study to compare the frequency of a broad spectrum of psychiatric disorders in children with 16p11.2 deletion and duplication. We aimed to evaluate (1) the nature and prevalence of psychopathology associated with copy number variation (CNV) in children with 16p11.2 by comparing deletion and duplication carriers with family controls; (2) ...[more]