Ontology highlight
ABSTRACT:
SUBMITTER: Niarchou M
PROVIDER: S-EPMC6341088 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Niarchou Maria M Chawner Samuel J R A SJRA Doherty Joanne L JL Maillard Anne M AM Jacquemont Sébastien S Chung Wendy K WK Green-Snyder LeeAnne L Bernier Raphael A RA Goin-Kochel Robin P RP Hanson Ellen E Linden David E J DEJ Linden Stefanie C SC Raymond F Lucy FL Skuse David D Hall Jeremy J Owen Michael J MJ Bree Marianne B M van den MBMVD
Translational psychiatry 20190116 1
Deletion and duplication of 16p11.2 (BP4-BP5) have been associated with an increased risk of intellectual disability and psychiatric disorder. This is the first study to compare the frequency of a broad spectrum of psychiatric disorders in children with 16p11.2 deletion and duplication. We aimed to evaluate (1) the nature and prevalence of psychopathology associated with copy number variation (CNV) in children with 16p11.2 by comparing deletion and duplication carriers with family controls; (2) ...[more]