Ontology highlight
ABSTRACT:
SUBMITTER: Takahashi H
PROVIDER: S-EPMC6343031 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Takahashi Hannah H Cornish Alex J AJ Sud Amit A Law Philip J PJ Disney-Hogg Linden L Calvocoressi Lisa L Lu Lingeng L Hansen Helen M HM Smirnov Ivan I Walsh Kyle M KM Schramm Johannes J Hoffmann Per P Nöthen Markus M MM Jöckel Karl-Heinz KH Schildkraut Joellen M JM Simon Matthias M Bondy Melissa M Wrensch Margaret M Wiemels Joseph L JL Claus Elizabeth B EB Turnbull Clare C Houlston Richard S RS
Scientific reports 20190122 1
Little is known about the causes of meningioma. Obesity and obesity-related traits have been reported in several epidemiological observational studies to be risk factors for meningioma. We performed an analysis of genetic variants associated with obesity-related traits to assess the relationship with meningioma risk using Mendelian randomization (MR), an approach unaffected by biases from temporal variability and reverse causation that might have affected earlier investigations. We considered 11 ...[more]