Predicting gastroesophageal varices through spleen magnetic resonance elastography in pediatric liver fibrosis.

ABSTRACT:

Background

A recent retrospective study confirmed that hepatic stiffness and splenic stiffness measured with magnetic resonance elastography (MRE) are strongly associated with the presence of esophageal varices. In addition, strong correlations have been reported between splenic stiffness values measured with MRE and hepatic venous pressure gradients in animal models. However, most studies have been conducted on adult populations, and previous pediatric MRE studies have only demonstrated the feasibility of MRE in pediatric populations, while the actual clinical application of spleen MRE has been limited.

Aim

To assess the utility of splenic stiffness measurements by MRE to predict gastroesophageal varices in children.

Methods

We retrospectively reviewed abdominal MRE

SUBMITTER: Yoon H 

PROVIDER: S-EPMC6343098 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature