Environmental Exposure History and Vulvodynia Risk: A Population-Based Study.
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ABSTRACT: Background
Risk factors for vulvodynia continue to be elusive. We evaluated the association between past environmental exposures and the presence of vulvodynia.Materials and methods
The history of 28 lifetime environmental exposures was queried in the longitudinal population-based Woman-to-Woman Health Study on the 24-month follow-up survey. Relationships between these and vulvodynia case status were assessed using multinomial logistic regression.Results
Overall, 1585 women completed the 24-month survey, the required covariate responses, and questions required for case status assessment. Screening positive as a vulvodynia case was associated with history of exposures to home-sprayed chemicals (insecticides, fungicides, herbicides-odds ratio [OR] 2.47, 95% confidence interval [CI] 1.71-3.58, p?ConclusionsThis preliminary evaluation suggests a positive association between vulvodynia and the reported history of exposures to a number of household and work-related environmental toxins. Further investigation of timing and dose of environmental exposures, relationship to clinical course, and treatment outcomes is warranted.
SUBMITTER: Reed BD
PROVIDER: S-EPMC6343193 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
Environmental Exposure History and Vulvodynia Risk: A Population-Based Study.
Reed Barbara D BD McKee Kimberly S KS Plegue Melissa A MA Park Sung Kyun SK Haefner Hope K HK Harlow Sioban D SD
Journal of women's health (2002) 20181010 1
<h4>Background</h4>Risk factors for vulvodynia continue to be elusive. We evaluated the association between past environmental exposures and the presence of vulvodynia.<h4>Materials and methods</h4>The history of 28 lifetime environmental exposures was queried in the longitudinal population-based Woman-to-Woman Health Study on the 24-month follow-up survey. Relationships between these and vulvodynia case status were assessed using multinomial logistic regression.<h4>Results</h4>Overall, 1585 wom ...[more]
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