Ontology highlight
ABSTRACT:
SUBMITTER: van den Hoogen LL
PROVIDER: S-EPMC6343524 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
van den Hoogen Lotus L LL Walk Jona J Oulton Tate T Reuling Isaie J IJ Reiling Linda L Beeson James G JG Coppel Ross L RL Singh Susheel K SK Singh Susheel K SK Draper Simon J SJ Bousema Teun T Drakeley Chris C Sauerwein Robert R Tetteh Kevin K A KKA
Frontiers in microbiology 20190116
The majority of malaria infections in low transmission settings remain undetectable by conventional diagnostics. A powerful model to identify antibody responses that allow accurate detection of recent exposure to low-density infections is controlled human malaria infection (CHMI) studies in which healthy volunteers are infected with the <i>Plasmodium</i> parasite. We aimed to evaluate antibody responses in malaria-naïve volunteers exposed to a single CHMI using a custom-made protein microarray. ...[more]