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Multivalency in Rab effector interactions.


ABSTRACT: Rab proteins regulate vesicular transport in eukaryotic cells and establish connections to various cellular structures and processes by interacting with so-called effector molecules. Several of these effectors are known to not only bind a single Rab protein, but to be able to bind multiple different Rabs simultaneously. In this review we will give a short overview of effectors in general and (putative) functions of the aforementioned multivalent Rab:effector interactions.

SUBMITTER: Rai A 

PROVIDER: S-EPMC6343607 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Multivalency in Rab effector interactions.

Rai Amrita A   Goody Roger S RS   Müller Matthias P MP  

Small GTPases 20170127 1


Rab proteins regulate vesicular transport in eukaryotic cells and establish connections to various cellular structures and processes by interacting with so-called effector molecules. Several of these effectors are known to not only bind a single Rab protein, but to be able to bind multiple different Rabs simultaneously. In this review we will give a short overview of effectors in general and (putative) functions of the aforementioned multivalent Rab:effector interactions. ...[more]

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