Ontology highlight
ABSTRACT:
SUBMITTER: Brinson RG
PROVIDER: S-EPMC6343768 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Brinson Robert G RG Marino John P JP Delaglio Frank F Arbogast Luke W LW Evans Ryan M RM Kearsley Anthony A Gingras Geneviève G Ghasriani Houman H Aubin Yves Y Pierens Gregory K GK Jia Xinying X Mobli Mehdi M Grant Hamish G HG Keizer David W DW Schweimer Kristian K Ståhle Jonas J Widmalm Göran G Zartler Edward R ER Lawrence Chad W CW Reardon Patrick N PN Cort John R JR Xu Ping P Ni Feng F Yanaka Saeko S Kato Koichi K Parnham Stuart R SR Tsao Desiree D Blomgren Andreas A Rundlöf Torgny T Trieloff Nils N Schmieder Peter P Ross Alfred A Skidmore Ken K Chen Kang K Keire David D Freedberg Darón I DI Suter-Stahel Thea T Wider Gerhard G Ilc Gregor G Plavec Janez J Bradley Scott A SA Baldisseri Donna M DM Sforça Mauricio Luis ML Zeri Ana Carolina de Mattos ACM Wei Julie Yu JY Szabo Christina M CM Amezcua Carlos A CA Jordan John B JB Wikström Mats M
mAbs 20181222 1
The increased interest in using monoclonal antibodies (mAbs) as a platform for biopharmaceuticals has led to the need for new analytical techniques that can precisely assess physicochemical properties of these large and very complex drugs for the purpose of correctly identifying quality attributes (QA). One QA, higher order structure (HOS), is unique to biopharmaceuticals and essential for establishing consistency in biopharmaceutical manufacturing, detecting process-related variations from manu ...[more]