Ontology highlight
ABSTRACT:
SUBMITTER: Picard E
PROVIDER: S-EPMC6343773 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Picard Emilie E Godet Yann Y Laheurte Caroline C Dosset Magalie M Galaine Jeanne J Beziaud Laurent L Loyon Romain R Boullerot Laura L Lauret Marie Joseph Elodie E Spehner Laurie L Jacquin Marion M Eberst Guillaume G Gaugler Béatrice B Le Pimpec-Barthes Françoise F Fabre Elizabeth E Westeel Virginie V Caignard Anne A Borg Christophe C Adotévi Olivier O
Oncoimmunology 20181019 2
Natural killer (NK) cells are innate effector lymphocytes widely involved in cancer immunosurveillance. In this study, we described three circulating NK cell subsets in patients with non-small cell lung cancer (NSCLC). Compared to healthy donors (HD), lower rate of the cytotoxic CD56<sup>dim</sup> CD16<sup>+</sup> NK cells was found in NSCLC patients (76.1% vs 82.4%, <i>P </i>= 0.0041). In contrast, the rate of CD56<sup>bright</sup> NK cells was similar between patients and HD. We showed in NSCL ...[more]