Ontology highlight
ABSTRACT:
SUBMITTER: Claeys C
PROVIDER: S-EPMC6344072 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Claeys Carine C Chandrasekaran Vijayalakshmi V García-Sicilia José J Prymula Roman R Díez-Domingo Javier J Brzostek Jerzy J Marès-Bermúdez Josep J Martinón-Torres Federico F Pollard Andrew J AJ Růžková Renata R Carmona Martinez Alfonso A Ulied Angels A Miranda Valdivieso Mariano M Faust Saul N SN Snape Matthew D MD Friel Damien D Ollinger Thierry T Soni Jyoti J Schuind Anne A Li Ping P Innis Bruce L BL Jain Varsha K VK
The Pediatric infectious disease journal 20190201 2
<h4>Background</h4>It has not yet been demonstrated whether 2 doses of inactivated quadrivalent influenza vaccine (IIV4) prime a booster response in infants. We evaluated the anamnestic immune response to an IIV4 in children 17-48 months of age.<h4>Methods</h4>Children were randomized to 2 doses of IIV4 or control in the primary phase III study (NCT01439360). One year later, in an open-label revaccination extension study (NCT01702454), a subset of children who received IIV4 in the primary study ...[more]