Ontology highlight
ABSTRACT:
SUBMITTER: Berg L
PROVIDER: S-EPMC6345483 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
PloS one 20190124 1
We show that in an animal model of anxiety the overall excitation, particularly in the infralimbic region of the medial prefrontal cortex (IL), is increased and that the activity ratio between excitatory pyramidal neurons and inhibitory interneurons (AR PN/IN) is shifted towards excitation. The same change in AR PN/IN is evident for wildtype mice, which have been exposed to an anxiety stimulus. We hypothesize, that an elevated activity and the imbalance of excitation (PN) and inhibition (IN) wit ...[more]