Ontology highlight
ABSTRACT:
SUBMITTER: Ruocco N
PROVIDER: S-EPMC6345956 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Ruocco Nadia N Annunziata Concetta C Ianora Adrianna A Libralato Giovanni G Manfra Loredana L Costantini Susan S Costantini Maria M
Scientific reports 20190124 1
Diatom-derived polyunsaturated aldehydes (PUAs), decadienal, heptadienal and octadienal, derive from the oxidation of fatty acids and have cytotoxic and anticancer effects. PUAs, tested separately, induce malformations in sea urchin Paracentrotus lividus embryos. Decadienal induces the worst malformations and lowest survival rates. Interestingly, decadienal, heptadienal and octadienal place in motion several genes to counteract their negative effects. To date, no studies are available reporting ...[more]