Ontology highlight
ABSTRACT:
SUBMITTER: Borlle L
PROVIDER: S-EPMC6346515 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Borlle Lucia L Dergham Abdo A Wund Zacharie Z Zumbo Brittany B Southard Teresa T Hume Kelly R KR
BMC veterinary research 20190124 1
<h4>Background</h4>Cancer is a significant health threat in cats. Chemoresistance is prevalent in solid tumors. The ionophore salinomycin has anti-cancer properties and may work synergistically with chemotherapeutics. The purpose of our study was to determine if salinomycin could decrease cancer cell viability when combined with doxorubicin in feline sarcoma and carcinoma cells.<h4>Results</h4>We established two new feline injection-site sarcoma cell lines, B4 and C10, and confirmed their tumori ...[more]