Ontology highlight
ABSTRACT:
SUBMITTER: Chen J
PROVIDER: S-EPMC6348090 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Chen Jie J Xing Chaofeng C Yan Li L Wang Yabing Y Wang Haosen H Zhang Zongmeng Z Yu Daolun D Li Jie J Li Honglin H Li Jun J Cai Yafei Y
PeerJ 20190124
ZBTB38 belongs to the zinc finger protein family and contains the typical BTB domains. As a transcription factor, ZBTB38 is involved in cell regulation, proliferation and apoptosis, whereas, functional deficiency of ZBTB38 induces the human neuroblastoma (NB) cell death potentially. To have some insight into the role of ZBTB38 in NB development, high throughput RNA sequencing was performed using the human NB cell line SH-SY5Y with the deletion of ZBTB38. In the present study, 2,438 differentiall ...[more]