Dataset Information

Does total volume of physical activity matter more than pattern for onset of CVD? A prospective cohort study of older British men.

ABSTRACT:

Aims

With increasing age, physical inactivity and sedentary behaviour levels increase, as does cardiovascular disease (CVD) incidence. We investigate how device-measured sedentary behaviour and physical activity (PA) are related to CVD onset in men aged 70+; whether the total volume of activity is more important than pattern.

Methods and results

Prospective population-based cohort study of men recruited from 24 UK General Practices in 1978-80. In 2010-12, 3137 survivors were invited to complete questionnaires and wear an Actigraph GT3x accelerometer for 7?days. PA intensity was categorised as sedentary, light and moderate to vigorous (MVPA). Men were followed up for Myocardial Infarction, stroke and heart failure (ICD9 410-414, 430-438 and 428) morbidity and mortality from 2010 to 12 to June 2016. Hazard Ratios (HRs) for incident Cardiovascular Disease (CVD) were estimated. 1528/3137 (49%) men had sufficient accelerometer data. 254 men with pre-existing CVD were excluded. Participants' mean age was 78.4 (range 71-92)?years. After median 4.9?years follow-up, 122 first CVD events occurred in 1181 men (22.7/1000?person-years) with complete data. For each additional 30?min in sedentary behaviour, light PA,10?min in MVPA, or 1000 steps/day, HRs for CVD were 1.09(95%CI 1.00, 1.19), 0.94(0.85, 1.04), 0.88(0.81, 0.96) and 0.86(0.78 to 0.95) respectively, adjusted for measurement-related factors, socio-demographics, health behaviours and disability. HRs for accumulating 150?min/week MVPA in bouts ?1?min and bouts ?10?min were 0.47(0.32 to 0.69), and 0.49(0.25, 0.98).

Conclusions

In older men, high volume of steps or MVPA rather than MVPA bouts was associated with reduced CVD risk.

SUBMITTER: Jefferis BJ

PROVIDER: S-EPMC6350006 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Publications

Does total volume of physical activity matter more than pattern for onset of CVD? A prospective cohort study of older British men.

Jefferis Barbara J BJ Parsons Tessa J TJ Sartini Claudio C Ash Sarah S Lennon Lucy T LT Papacosta Olia O Morris Richard W RW Wannamethee S Goya SG Lee I-Min IM Whincup Peter H PH

International journal of cardiology 20181213

<h4>Aims</h4>With increasing age, physical inactivity and sedentary behaviour levels increase, as does cardiovascular disease (CVD) incidence. We investigate how device-measured sedentary behaviour and physical activity (PA) are related to CVD onset in men aged 70+; whether the total volume of activity is more important than pattern.<h4>Methods and results</h4>Prospective population-based cohort study of men recruited from 24 UK General Practices in 1978-80. In 2010-12, 3137 survivors were invit ...[more]

PMID: 30578094

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Dataset Information

Does total volume of physical activity matter more than pattern for onset of CVD? A prospective cohort study of older British men.

Aims

Methods and results

Conclusions

Publications

Does total volume of physical activity matter more than pattern for onset of CVD? A prospective cohort study of older British men.

Similar Datasets

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