Ontology highlight
ABSTRACT:
SUBMITTER: Parker EPK
PROVIDER: S-EPMC6350944 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Parker Edward P K EPK Whitfield Helena H Baskar Chudarkodi C Giri Sidhartha S John Jacob J Grassly Nicholas C NC Kang Gagandeep G Praharaj Ira I
The Journal of infectious diseases 20190101 4
FUT2 determines whether histo-blood group antigens are secreted at mucosal surfaces. Secretor status influences susceptibility to enteric viruses, potentially including oral poliovirus vaccine (OPV). We performed a nested case-control study to determine the association between FUT2 genotype (single-nucleotide polymorphisms G428A, C302T, and A385T) and seroconversion among Indian infants who received a single dose of monovalent type 3 OPV. Secretor prevalence was 75% (89 of 118) in infants who se ...[more]