Ontology highlight
ABSTRACT:
SUBMITTER: Forrest SL
PROVIDER: S-EPMC6351353 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Forrest Shelley L SL Halliday Glenda M GM McCann Heather H McGeachie Andrew B AB McGinley Ciara V CV Hodges John R JR Piguet Olivier O Kwok John B JB Spillantini Maria G MG Kril Jillian J JJ
Alzheimer's & dementia (Amsterdam, Netherlands) 20190124
<h4>Introduction</h4>Exploring the degree of heritability in a large cohort of frontotemporal lobar degeneration with tau-immunopositive inclusions (FTLD-tau) and determining if different FTLD-tau subtypes are associated with stronger heritability will provide important insight into disease pathogenesis.<h4>Methods</h4>Using modified Goldman pedigree classifications, heritability was examined in pathologically proven FTLD-tau cases with dementia at any time (n = 124) from the Sydney-Cambridge co ...[more]