Impact of Erythropoiesis-Stimulating Agents on Behavioral Measures in Children Born Preterm.

ABSTRACT:

Objective

To evaluate the impact of erythropoiesis-stimulating agents (ESAs) administered during initial hospitalization and family demographic factors on behavior at 3.5-4 years of age.

Study design

Children were enrolled who had previously participated in a randomized study of ESAs (n = 35) or placebo (n = 14) in infants born preterm with birth weights of 500-1250 g. A term healthy control group (n = 22) also was recruited. Behavior was evaluated by parent report with the Behavioral Assessment System of Children-2. Principal component analyses identified 2 demographic factors, a Socioeconomic Composite (SEC) and a Family Stress Composite. A multivariate general linear model evaluated the impact of study group and sex on the 4 composite scales of the Behavioral Assessment S

SUBMITTER: Lowe JR 

PROVIDER: S-EPMC6352724 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature