Ontology highlight
ABSTRACT:
SUBMITTER: Ghatan S
PROVIDER: S-EPMC6353460 | biostudies-literature | 2016 May-Jun
REPOSITORIES: biostudies-literature
Ghatan Saadi S Kokoszka Malgosia A MA Ranney Anne M AM Strauss Kevin A KA
Movement disorders clinical practice 20160105 3
Two individuals with intractable generalized dystonia secondary to glutaric aciduria type 1 (GA1) were treated with continuous intraventricular baclofen (IVB) infusion. On IVB of 220 μg/day, one 10-year-old girl had an 85% reduction in dystonia, from Barry-Albright Dystonia Scale (BADS) score 30.7 to 4.5 (maximum score: 32) at 30 postoperative months. Her enteral dystonia medications were reduced >60%, and she discontinued medications for pain, anxiety, and depression. A second GA1 patient, age ...[more]