Ontology highlight
ABSTRACT:
SUBMITTER: Nevenzal H
PROVIDER: S-EPMC6353932 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Nevenzal Hadas H Noach-Hirsh Meirav M Skornik-Bustan Or O Brio Lev L Barbiro-Michaely Efrat E Glick Yair Y Avrahami Dorit D Lahmi Roxane R Tzur Amit A Gerber Doron D
Communications biology 20190130
Autophosphorylation of receptor and non-receptor tyrosine kinases is a common molecular switch with broad implications for pathogeneses and therapy of cancer and other human diseases. Technologies for large-scale discovery and analysis of autophosphorylation are limited by the inherent difficulty to distinguish between phosphorylation and autophosphorylation in vivo and by the complexity associated with functional assays of receptors kinases in vitro. Here, we report a method for the direct dete ...[more]