Hypoxic and Cold Adaptation Insights from the Himalayan Marmot Genome.
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ABSTRACT:
SUBMITTER: Bai L
PROVIDER: S-EPMC6354217 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
Hypoxic and Cold Adaptation Insights from the Himalayan Marmot Genome.
Bai Liang L Liu Baoning B Ji Changmian C Zhao Sihai S Liu Siyu S Wang Rong R Wang Weirong W Yao Pu P Li Xuming X Fu Xiaojun X Yu Haiyan H Liu Min M Han Fengming F Guan Ning N Liu Hui H Liu Dongyuan D Tao Yuanqing Y Wang Zhongdong Z Yan Shunsheng S Florant Greg G Butcher Michael T MT Zhang Jifeng J Zheng Hongkun H Fan Jianglin J Enqi Liu
iScience 20181220
The Himalayan marmot (Marmota himalayana) is a hibernating mammal that inhabits the high-elevation regions of the Himalayan mountains. Here we present a draft genome of the Himalayan marmot, with a total assembly length of 2.47 Gb. Phylogenetic analyses showed that the Himalayan marmot diverged from the Mongolian marmot approximately 1.98 million years ago. Transcriptional changes during hibernation included genes responsible for fatty acid metabolism in liver and genes involved in complement an ...[more]
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