Annotation of gene product function from high-throughput studies using the Gene Ontology.
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ABSTRACT:
SUBMITTER: Attrill H
PROVIDER: S-EPMC6355445 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
Annotation of gene product function from high-throughput studies using the Gene Ontology.
Attrill Helen H Gaudet Pascale P Huntley Rachael P RP Lovering Ruth C RC Engel Stacia R SR Poux Sylvain S Van Auken Kimberly M KM Georghiou George G Chibucos Marcus C MC Berardini Tanya Z TZ Wood Valerie V Drabkin Harold H Fey Petra P Garmiri Penelope P Harris Midori A MA Sawford Tony T Reiser Leonore L Tauber Rebecca R Toro Sabrina S
Database : the journal of biological databases and curation 20190101
High-throughput studies constitute an essential and valued source of information for researchers. However, high-throughput experimental workflows are often complex, with multiple data sets that may contain large numbers of false positives. The representation of high-throughput data in the Gene Ontology (GO) therefore presents a challenging annotation problem, when the overarching goal of GO curation is to provide the most precise view of a gene's role in biology. To address this, representatives ...[more]
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