Ontology highlight
ABSTRACT:
SUBMITTER: Porat-Shliom N
PROVIDER: S-EPMC6355620 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Porat-Shliom Natalie N Harding Olivia J OJ Malec Lenka L Narayan Kedar K Weigert Roberto R
iScience 20190104
Mitochondria are dynamic organelles undergoing fission, fusion, and translocation. These processes have been studied in cultured cells; however, little is known about their regulation in cells within tissues in vivo. We applied four-dimensional intravital microscopy to address this in secretory cells of the salivary gland. We found that mitochondria are organized in two populations: one juxtaposed to the basolateral plasma membrane and the other dispersed in the cytosol. Under basal conditions, ...[more]